According to our computer model, the Buffalo Bills will defeat the Las Vegas Raiders when they play at Highmark Stadium on Sunday, September 17 (at 1:00 PM ET). We have a complete breakdown, regarding the point spread, total and final score, available below.

The Bills ranked sixth in total defense last season (319.1 yards allowed per game), but they thrived on offense, ranking second-best in the NFL with 397.6 total yards per game. From an offensive standpoint, the Raiders ranked 12th in the NFL with 23.2 points per game last season. Meanwhile, they ranked 26th in points allowed (365.6 points allowed per contest).

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Bills vs. Raiders Predictions and Picks

ATS Over/Under Score Prediction
Bills (-7.5) Under (46.5) Bills 23, Raiders 13

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Bills Betting Info

  • The Bills have an implied moneyline win probability of 78.9% in this contest.
  • Buffalo compiled a 7-8-0 record against the spread last season.
  • The Bills had an ATS record of 5-5 when playing as at least 7.5-point favorites last season.
  • Last season, the combined scoring went over the point total six times in Buffalo games.
  • The point total average for Bills games last season was 47.7, 1.2 points higher than the over/under for this matchup.

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Raiders Betting Info

  • The Raiders have a 25.6% chance to win this game based on the implied probability of the moneyline.
  • Las Vegas won eight games against the spread last season, failing to cover nine times.
  • The Raiders covered the spread once when an underdog by 7.5 points or more last season (in two opportunities).
  • Las Vegas and its opponent combined to hit the over nine out of 17 times last season.
  • The over/under for this game is 0.1 points higher than the average scoring total for Raiders games last season (46.4).

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Bills vs. Raiders 2022 Scoring Insights

Pts Pts Allowed Home Pts Home Pts Allowed Away Pts Away Pts Allowed
Buffalo 28.4 17.9 31.8 18.4 25.1 17.4
Las Vegas 23.2 24.6 27.1 26.1 19.8 23.2

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